Conceptually similarJuan GaertnerActivation (and inhibition) of the immune response on T-cellsSS21586777Juan GaertnerActivation (and inhibition) of the immune response on T-cellsSS21586788Juan GaertnerThe protein PD-1 is a checkpoint to slow down T-cells.SS21586734Juan GaertnerDendritic cell presenting an antigen to T-lymphocytesSS21289223Juan GaertnerIsolated view of a T-cell receptor in complex with the MHC class II-peptide complexSS21286841Juan GaertnerClose up view of a T-cell receptor in complex with the MHC class II-peptidSS21287127Juan GaertnerT-cell receptor in complex with the MHC class II-peptide complexSS21287128Juan GaertnerDendritic cell presenting an antigen to T-cellsSS21311497Juan GaertnerDendritic cellSS21287129View AllView more with similar tones Antibody blocking PD-1 proteinsLicense type:Rights ManagedUnique identifier:SS21586689Description:Antibody blocking PD-1 to avoid the down-regulation of the immune system by cancer cells. Cancer cells express PD-L1 (orange) proteins on their surface to trick the immune system. The interaction of PD-L1 with PD-1 of T-cells leads to a down-regulation of T-cells. The antibody (yellow) blocks this interaction.Credit:Juan Gaertner/Science SourceSize:8000px × 6000px (~137 MB)Get PricingHow Will The Visual Be Used?ShareRelated Virtual folders:3D Medical ImagesKeywords:accessory cell-adaptive immunity-antigen-antigen presentation-antigen-presenting cells-cancer-cancer prevention-cancer therapy-cell membrane-co-stimulation-cytotoxic-cytotoxic t cell-dendritic cell-disease-down-regulation-helper t cell-human cell-illness-immune defense-immune system-immunity-innate immunity-interferon-killer cell-lymphocyte-major histocompatibility complex-malignant cell-medicine-metastasis-mhc class-mhc-complex-molecules-natural-pd-1-pd-l1-peptide-programmed cell death protein-protein-receptor-signal cascade-signal transduction-t cell-vaccination-wbc-white cellFolder Legacy Identifier:SS2CT84082_20181016Model release:N/AParent folder:2018-10-16